I'm not very good with official classifications, but I guess I'd consider us a higher-end second tier (in terms of prestige) R1 state university. The field is Cognitive Neuroscience and compared to some of the higher-tier schools $225K is actually pretty low; however, he startup is on par with the dept's recent hires, although significantly lower than those given in the bio-themed departments. The $ will primarily go towards developing the fMRI and EEG components of my research program.
Ultimately, I don;t the the absolute $ amount is what is important. Instead, what is important is that you have the resources YOU need to get YOUR research program on track. For me, $225K is sufficient, for others it will be too little and for others too much.
I think it really boils down to what your research goals are and what the expectations of the school are.
If you are getting hired to do high priced research, you should expect to get a large startup package.